So far, so good.

I've had this LaCie Quadra for about two months now, and so far, so good.

The pros:
1. Easy setup (after all, it's just an external HD)
2. Ability to use Firewire 800. I have this external HD hooked up to my Mac laptop running Mac OS X 10.5. The Time Machine feature, although unobtrusive, does take some time for its backups, so the ability to use FW800 instead of FW400 or USB2.0 probably saves some time (although this is only a guess, as I haven't tested those other two connections). The other secondary benefit of using FW800 is that it keeps a spare FW400 port open on my computer (not a big deal from a functional standpoint, since you can daisy-chain firewire devices, but it helps from a convenience standpoint).
3. Nice aesthetics. Small upright footprint. The silver metal wire mesh case matches perfectly with my MacBookPro and extermal Apple monitor. It also has a cool blue light.

Cons:
None so far.

In summary, basically an easy and attractive way to add 1TB of storage.  more

Easy as Pie

I'm an end-user, not a real tech-person. And there is nothing I love better than a product that tells you to plug it in and it will work just fine. I did and it does. Suddenly I have a terrabyte of trustworthy storage on my desk for my years and years of digital and digitalized photos. (I have been shooting RAW for two years and my "C" drive was gagging.) I also store off-site but it is a pleasure to tell Lightroom and Photoshop to look for the good stuff on my LaCie. And, when I finally decide to switch over to a MAC some day,the LaCie can quickly change its loyalty with me.

Expensive but high quality

I ordered this 1TB hard drive to backup my pictures, music and movies form other hard drives with Carbon Copy Cloner. I like the multiple interface I can daisy chain my 500GB rugged to the FW800 port and works perfectly. I didn't install the backup softwares since they are not compatible with Leopard. The HD turns off automatically when I eject it from Finder which is a good feature but sadly the supplied cables are too short so you won't be able to hide the drive under your desk...